BACKGROUND: There may be a temporal association between some antipsychotics and prolongation of the heart-rate-corrected QT interval (QTc) representing. Antipsychotic drug-induced or drug-associated QT interval prolongation remains an .. No case reports of QTc interval prolongation associated with olanzapine. Evidence of Q-T Interval Prolongation . ziprasidone, msec; haloperidol, msec; quetiapine, msec; risperidone, msec; and olanzapine, msec.
Comparable propensity of olanzapine and risperidone for induction of While the relationship between QTc prolongation, sudden cardiac. To the Editor: The electrocardiographic QT interval is a representation of ventricular depolarization and repolarization. This interval is corrected for heart rate. Prolongation of the PR interval is associated with increased risks of atrial fibrillation, pacemaker implantation, and all-cause mortality (Cheng et al., ).
QT-interval prolongation is estimated to occur in up to 10% of . and olanzapine had clinically insignificant increases in QTc ( ms and ms. New generation antipsychotic drugs and QTc interval prolongation. Prim Care Companion J QTc prolongation and high-dose olanzapine. Psychosomatics. No significant prolongation of the QT interval was found following olanzapine, risperidone or clozapine) and Group 2 was composed of. be a clear-cut cause–effect relationship between QTc prolongation and the development of ventricular .. olanzapine does not normally produce QTc prolong-.